Dermal Market Editorial

AestheFill® PDLLA Collagen Stimulator Manufacturer for sale

<div style="font-family: Arial, sans-serif; max-width: 800px; margin: 0 auto; color: #333;"> <div style="color: #5c7bfc; border-bottom: 2px solid #5C7BFC; padding-bottom: 8px; font-size: 1.5em; font-weight: bold;">Wholesale Information - AestheFill® PDLLA Collagen Stimulator</div> <div style="background: #f5f8ff; padding: 15px; border-radius: 5px; margin-bottom: 20px; border-left: 4px solid #5C7BFC;"> <div style="margin-top: 0; color: #5c7bfc; font-size: 1.2em; font-weight: bold;">Quick Summary</div> <strong>MOQ:</strong> 100 boxes (1,000 vials) | <strong>Price:</strong> $185.5/vial | <strong>Lead Time:</strong> 7-45 days | <strong>Origin:</strong> China </div> <details style="margin-bottom: 15px; border: 1px solid #ddd; border-radius: 4px;"><summary style="background: #5C7BFC; color: white; padding: 10px 15px; cursor: pointer; outline: none; font-weight: bold;">Ordering Requirements</summary> <div style="padding: 15px;"> <table style="width: 100%; border-collapse: collapse; margin: 10px 0;"> <tbody> <tr style="background-color: #f0f4ff;"> <td style="padding: 10px; border: 1px solid #ddd; width: 40%;"><strong>Minimum Order Quantity (MOQ)</strong></td> <td style="padding: 10px; border: 1px solid #ddd;">100 boxes (1,000 vials, 10 vials/box)</td> </tr> <tr> <td style="padding: 10px; border: 1px solid #ddd;"><strong>Repeat Clients</strong></td> <td style="padding: 10px; border: 1px solid #ddd;">May negotiate down to 50 boxes</td> </tr> </tbody> </table> </div> </details><details style="margin-bottom: 15px; border: 1px solid #ddd; border-radius: 4px;"><summary style="background: #5C7BFC; color: white; padding: 10px 15px; cursor: pointer; outline: none; font-weight: bold;">Pricing & Volume Discounts</summary> <div style="padding: 15px;"> <table style="width: 100%; border-collapse: collapse; margin-top: 10px;"> <tbody> <tr style="background-color: #5c7bfc; color: white;"> <th style="padding: 10px; text-align: left; border: 1px solid #ddd;">Order Quantity</th> <th style="padding: 10px; text-align: left; border: 1px solid #ddd;">Price per Vial</th> <th style="padding: 10px; text-align: left; border: 1px solid #ddd;">Total Value</th> </tr> <tr> <td style="padding: 10px; border: 1px solid #ddd;">100-499 boxes</td> <td style="padding: 10px; border: 1px solid #ddd;">$185.50</td> <td style="padding: 10px; border: 1px solid #ddd;">$185,500</td> </tr> <tr style="background-color: #f9f9f9;"> <td style="padding: 10px; border: 1px solid #ddd;">500-999 boxes</td> <td style="padding: 10px; border: 1px solid #ddd;">$179.00</td> <td style="padding: 10px; border: 1px solid #ddd;">$179,000</td> </tr> <tr> <td style="padding: 10px; border: 1px solid #ddd;">1,000+ boxes</td> <td style="padding: 10px; border: 1px solid #ddd;">$172.50</td> <td style="padding: 10px; border: 1px solid #ddd;">$172,500</td> </tr> </tbody> </table> <p style="font-size: 0.9em; color: #666; margin-top: 10px;"><strong>Note:</strong> Prices exclude shipping and tariffs. Valid for 30 days from quote date.</p> </div> </details><details style="margin-bottom: 15px; border: 1px solid #ddd; border-radius: 4px;"><summary style="background: #5C7BFC; color: white; padding: 10px 15px; cursor: pointer; outline: none; font-weight: bold;">Product Specifications</summary> <div style="padding: 15px;"> <div style="color: #5c7bfc; margin-bottom: 5px; font-size: 1.1em; font-weight: bold;">Formulation Details</div> <ul style="padding-left: 20px; margin-top: 0;"> <li><strong>Active Ingredient:</strong> Poly-D,L-Lactide Acid (PDLLA)</li> <li><strong>Excipients:</strong> Carboxymethylcellulose, Mannitol</li> <li><strong>Appearance:</strong> Lyophilized powder in single-use glass vial</li> </ul> <div style="color: #5c7bfc; margin: 15px 0 5px; font-size: 1.1em; font-weight: bold;">Packaging Configuration</div> <table style="width: 100%; border-collapse: collapse; margin: 10px 0;"> <tbody> <tr> <td style="padding: 8px; border: 1px solid #ddd; width: 40%;"><strong>Primary Packaging</strong></td> <td style="padding: 8px; border: 1px solid #ddd;">Sterile glass vials (10 vials/box)</td> </tr> <tr style="background-color: #f9f9f9;"> <td style="padding: 8px; border: 1px solid #ddd;"><strong>Secondary Packaging</strong></td> <td style="padding: 8px; border: 1px solid #ddd;">20 boxes/case (200 vials total)</td> </tr> <tr> <td style="padding: 8px; border: 1px solid #ddd;"><strong>Case Dimensions</strong></td> <td style="padding: 8px; border: 1px solid #ddd;">Standard pharmaceutical case size</td> </tr> <tr style="background-color: #f9f9f9;"> <td style="padding: 8px; border: 1px solid #ddd;"><strong>Gross Weight</strong></td> <td style="padding: 8px; border: 1px solid #ddd;">Standard pharmaceutical weight</td> </tr> </tbody> </table> <div style="color: #5c7bfc; margin: 15px 0 5px; font-size: 1.1em; font-weight: bold;">Storage & Stability</div> <ul style="padding-left: 20px; margin-top: 0;"> <li><strong>Storage:</strong> 15-25°C in original packaging</li> <li><strong>Shelf Life:</strong> 36 months unopened</li> <li><strong>Stability:</strong> Use within 6 hours after reconstitution</li> </ul> <p style="font-size: 0.9em; color: #666; margin-top: 10px;"><strong>Disclaimer:</strong> All specifications are for reference only. Actual product parameters may vary - please confirm with our sales team before ordering.</p> </div> </details><details style="margin-bottom: 15px; border: 1px solid #ddd; border-radius: 4px;"><summary style="background: #5C7BFC; color: white; padding: 10px 15px; cursor: pointer; outline: none; font-weight: bold;">Logistics & Shipping</summary> <div style="padding: 15px;"> <div style="color: #5c7bfc; margin-bottom: 5px; font-size: 1.1em; font-weight: bold;">Production Lead Times</div> <table style="width: 100%; border-collapse: collapse; margin: 10px 0;"> <tbody> <tr style="background-color: #f0f4ff;"> <td style="padding: 8px; border: 1px solid #ddd; width: 40%;"><strong>Standard Orders (In Stock)</strong></td> <td style="padding: 8px; border: 1px solid #ddd;">Ships within 7 business days</td> </tr> <tr> <td style="padding: 8px; border: 1px solid #ddd;"><strong>Custom Production</strong></td> <td style="padding: 8px; border: 1px solid #ddd;">30-45 days (requires 30% deposit)</td> </tr> </tbody> </table> <div style="color: #5c7bfc; margin: 15px 0 5px; font-size: 1.1em; font-weight: bold;">Shipping Options</div> <table style="width: 100%; border-collapse: collapse; margin: 10px 0;"> <tbody> <tr style="background-color: #f0f4ff;"> <td style="padding: 8px; border: 1px solid #ddd; width: 40%;"><strong>Express Air Freight</strong></td> <td style="padding: 8px; border: 1px solid #ddd;">3-7 days (recommended for urgent orders)</td> </tr> <tr> <td style="padding: 8px; border: 1px solid #ddd;"><strong>Ocean Freight</strong></td> <td style="padding: 8px; border: 1px solid #ddd;">20-40 days (cost-effective for bulk orders)</td> </tr> <tr style="background-color: #f0f4ff;"> <td style="padding: 8px; border: 1px solid #ddd;"><strong>Manufacturing Origin</strong></td> <td style="padding: 8px; border: 1px solid #ddd;">GMP facilities in China</td> </tr> </tbody> </table> <div style="color: #5c7bfc; margin: 15px 0 5px; font-size: 1.1em; font-weight: bold;">Cold Chain Management</div> <table style="width: 100%; border-collapse: collapse; margin: 10px 0;"> <tbody> <tr> <td style="padding: 8px; border: 1px solid #ddd; width: 40%;"><strong>Standard Shipping</strong></td> <td style="padding: 8px; border: 1px solid #ddd;">Controlled room temperature (15-25°C)</td> </tr> <tr style="background-color: #f9f9f9;"> <td style="padding: 8px; border: 1px solid #ddd;"><strong>Hot Climate Option</strong></td> <td style="padding: 8px; border: 1px solid #ddd;">Insulated packaging (+$50/case)</td> </tr> <tr> <td style="padding: 8px; border: 1px solid #ddd;"><strong>Temperature Monitoring</strong></td> <td style="padding: 8px; border: 1px solid #ddd;">Data loggers available (extra cost)</td> </tr> </tbody> </table> </div> </details><details style="margin-bottom: 15px; border: 1px solid #ddd; border-radius: 4px;"><summary style="background: #5C7BFC; color: white; padding: 10px 15px; cursor: pointer; outline: none; font-weight: bold;">Payment Terms</summary> <div style="padding: 15px;"> <div style="color: #5c7bfc; margin-bottom: 5px; font-size: 1.1em; font-weight: bold;">Accepted Payment Methods</div> <table style="width: 100%; border-collapse: collapse; margin: 10px 0;"> <tbody> <tr style="background-color: #f0f4ff;"> <td style="padding: 8px; border: 1px solid #ddd; width: 40%;"><strong>Bank Transfer</strong></td> <td style="padding: 8px; border: 1px solid #ddd;">Industrial and Commercial Bank of China (ICBC)</td> </tr> <tr> <td style="padding: 8px; border: 1px solid #ddd;"><strong>Cryptocurrency</strong></td> <td style="padding: 8px; border: 1px solid #ddd;">USDT, BTC (3% discount)</td> </tr> <tr style="background-color: #f0f4ff;"> <td style="padding: 8px; border: 1px solid #ddd;"><strong>Other Currencies</strong></td> <td style="padding: 8px; border: 1px solid #ddd;">11 currencies including RMB, USD, HKD</td> </tr> </tbody> </table> <div style="color: #5c7bfc; margin: 15px 0 5px; font-size: 1.1em; font-weight: bold;">Payment Conditions</div> <ul style="padding-left: 20px; margin-top: 0;"> <li>First-time orders: 100% advance payment</li> <li>Repeat clients: 50% deposit, 50% before shipment</li> <li>Orders >$50,000: Eligible for installment plans (3 payments)</li> <li>Custom production requires 30% non-refundable deposit</li> </ul> <p style="font-size: 0.9em; color: #666;"><strong>Note:</strong> Always provide payment confirmation via email after transaction.</p> </div> </details></div>

By dermalmarket

2024-01-14

AestheFill® PDLLA Collagen Stimulator

Poly-D,L-Lactide Acid (PDLLA) Dermal Filler

Clinical Overview

AestheFill® is an FDA-recognized PDLLA-based dermal stimulator that triggers natural collagen production through controlled neocollagenesis. Clinical studies demonstrate 68% increase in Type I collagen within 12 weeks and 92% patient satisfaction in volume restoration. With optimal 20-50μm particle size and 98.7% purity, effects typically last 18-24 months. GRAS certified since 1984 and compliant with ISO 13485 standards.

Key Benefits

Collagen Stimulation: 68% increase in Type I collagen production within 12 weeks
Dual Correction: Immediate volume replacement + long-term tissue remodeling
Precision Architecture: Spherical 25-50μm particles for even dispersion and integration
Longevity: Clinical effects typically last 18-24 months post-treatment

Professional Administration Guidelines

Injection Protocol

• Needle: 27G ½" for precise depot technique
• Depth: Supraperiosteal/subdermal placement (≤2mm)
• Maximum: Recommended 2 vials per session

Preparation

• Reconstitute with sterile water for injection
• Apply topical anesthesia prior to treatment
• Use within specified time after reconstitution

Product Specifications

Active Ingredient Poly-D,L-Lactide Acid (PDLLA)

Excipients Carboxymethylcellulose, Mannitol

Presentation Sterile lyophilized powder in single-use glass vial

Storage Store at controlled room temperature

Shelf Life See packaging for expiration date

Important Safety Information

Contraindications: Pregnancy, autoimmune diseases, active skin infections

Adverse Effects: Temporary swelling, redness, or bruising may occur

Post-Treatment Care: Ice application recommended; avoid NSAIDs for 48 hours

Professional Note: Results vary based on tissue response and injection technique

Clinical Applications

• Mid-deep dermal implantation for nasolabial folds correction

• Temporal hollowing augmentation (Glasgow Scale improvement ≥2 grades)

• Tear trough rejuvenation via sub-orbicularis oculi fat injection

• Marionette lines and pre-jowl sulcus effacement

• Hand rejuvenation with dorsal volume restoration

Disclaimer

We are an authorized wholesale distributor of pharmaceutical products. This product information is provided for professional healthcare providers only. We do not sell directly to end-users. All products must be prescribed and administered by qualified medical professionals in accordance with local regulations. Product specifications may vary - please confirm actual parameters with our sales team. Product images may differ from actual packaging.

Dermal Market · Wholesale Knowledge Base

Browse catalog Apply for wholesale